Gluconeogenesis is a metabolic process in which glucose is generated from non-carbohydrate carbon substrates.
Which one of the following substrates does NOT share its carbon in glucose skeleton but rather contributes as an energy source for gluconeogenesis?
A- Acetyl CoA
B- Alpha-ketoglutarate
C- Fumarate
D- Oxaloacetate
E- Succinyl CoA
Answer:
Acetyl CoA is an energy source as it generates 12 ATP for each citric acid cycle. Other substrates contribute their carbon in glucose skeleton.
The correct answer is A